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Description

16,17 It is unclear whether B12 is absorbed via the oral mucosa or in the small intestine with sublingual administration, and research into this question is scarce

All statistical tests will be performed with intention to treat and per protocol

all helping to lower inflammation levels over time

A diagnostic trial utilizing physiologic doses of vitamin B12 (1 mcg daily) and observing daily reticulocyte counts after establishing a baseline may also be performed